Category: Haematology Case Studies
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Acute Pancreatitis in a Child with Sickle Cell Disease
Sickle cell disease (SCD) is one of the common hemoglobinopathies around the world. It is characterized by a wide spectrum of complications that vary in severity. Vaso-occlusive crisis is the most common complication and accounts for the majority of admissions, while acute chest syndrome and sepsis are responsible for most of sickle cell-related mortalities. One…
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Novel Adenosine Deaminase 2 (ADA2) Mutations Associated with Haematological Manifestations
Deficiency of adenosine deaminase 2 (DADA2) is an autoinflammatory disorder characterized by various forms of vasculitis and is rarely manifesting as pure red cell aplasia (PRCA) or neutropenia. Very few reports in the literature document these associations. We, therefore, report two different novel mutations in the ADA2 (also known as cat eye syndrome chromosome region…
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Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anaemia
A 9-year-old Saudi girl was presented to our hospital with a fever of 38.5 °C, cough, and shortness of breath. Her oxygen saturation was 88% on room air; her blood pressure was normal for her age (110/75 mmHg); and she had no tachycardia (80 beats/minute). She had had abdominal pain for 2 days that was…